Flusilazole
   
Introduction: Flusilazole is a systemic fungicide with protective and curative action. Its resistance to wash-off, redistribution by rainfall and vapour phase activity are important components in its biological activity. Flusilazole is a broad spectrum, systemic, preventive and curative fungicide effective against many pathogens (Ascomycetes, Basidiomycetes and Deuteromycetes). It is recommended for use on many crops, such as: apples(Venturia inaequalis, Podosphaera leucotricha); peaches(Sphaerotheca pannosa, Monilia laxa); cereals(all major diseases); grapes(Uncinula necator, Guignardia bidwellii); sugar beet(Cercospora beticola, Erysiphe betae); maize(Helminthosporium turcicum); sunflowers(Phomopsis helianthi); oilseed rape(Pseudocercosporella capsellae, Pyrenopeziza brassicae); bananas(Mycosphaerella spp.).
Common name: Flusilazole
Another name: Flusilazol; Nustar; Sanction; Fluzilazol; Olymp; unch; Flusilazole [ISO]; DPX-H 6573; Punch 40EC; Caswell No. 419K; UNII-F3WG2VVD87; DPD 78710F; DPX 6573; etc.
Chemical name: bis(4-fluorophenyl)(methyl)(1H-1,2,4-triazol-1-ylmethyl)silane
Empirical formula: C16H15F2N3Si
Structural formula:
Mol. Weight: 315.39 g/mol
CAS No.: 85509-19-9
Specifications
Leading Flusilazole supplier
Flusilazole 95% TC
Flusilazole 250 g/L EC
Flusilazole 400 g/L EC
Packing:
BULK PACKING
Powder: 25kg/Bag, 25kg/Drum, 50kg/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum etc.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized packing label
Flusilazole FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H302 (100%): Harmful if swallowed.
H351 (100%): Suspected of causing cancer.
H360 (100%): May damage fertility or the unborn child.
H411 (100%): Toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P281: Use personal protective equipment as required.
P301+P312: IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
P308+P313: IF exposed or concerned: Get medical advice/attention.
P330: Rinse mouth.
P391: Collect spillage. Hazardous to the aquatic environment.
P405: Rinse mouth.
P501: Dispose of contents/container in accordance with local/regional/national/ international regulations.
Supplemental Hazard Statements: none.
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rats is 674 mg/kg. 2) Acute dermal LD50 for rats is >2000 mg/kg. 3) Acute inhalation toxicity LC50 (4 h) for rats is 2.7 mg/L. 4) Skin irritation: Non-irritating to skin (rabbits). 5) Eye irritation: Non-irritating to eyes (rabbits). 6) Skin sensitization for guinea pig: Non-sensitizing.
NOEL: (104 w) for rats is 2 mg/kg/day; (2 y) for mice is 3.4 mg/kg/day; (1 y) for dogs is 0.7 mg/kg/day. Other Not carcinogenic. Not genotoxic.
ADI (JMPR) 0-0.007 mg/kg b.w. [2007]
Classification:
WHO Classification: II (Moderately hazardous)
EC Risk Classification: Carcinogen category 3: R40; Reproduction risk category 2: R61; Xn - Harmful: R22; N - Dangerous for the environment: R51, R53
US EPA Classification (formulation): No consensus across products or no products available.
ECOTOXICOLOGY
Effect on birds: Acute oral LD50 (8 d) for Mallard is >1590 mg/kg. Effect on fish: Acute LC50 (96 h) for Rainbow trout is 1.2 mg/l. Effects on aquatic invertebrates: Acute EC50 (48 h) for Daphnia magna is 3.4 mg/l. Effects on algae: Acute 72 hour EC50 for Selenestrum capricornutum is 6.4 mg/l. Effects on bees: contact acute 48 hour LD50 is 165 g/bee, oral acute 48 hour LD50 is 33.8 g/bee. Effects on earthworms: Acute 14 day LC50 is 388 mg/kg.
ENVIRONMENTAL FATE
Soil/Environment Results of several different studies under varying environmental conditions indicate average DT50 95 d.
Usage: Flusilazole is an organosilicon fungicide invented by DuPont, which is used to control fungal infections on a variety of fruit and vegetable crops.
Application: Biochemistry Inhibits ergosterol biosynthesis (steroid demethylation inhibitor). Mode of action Systemic fungicide with protective and curative action. Its resistance to wash-off, redistribution by rainfall and vapour phase activity are important components in its biological activity. Uses Broad spectrum, systemic, preventive and curative fungicide effective against many pathogens (Ascomycetes, Basidiomycetes and Deuteromycetes). It is recommended for use on many crops, such as: apples (Venturia inaequalis, Podosphaera leucotricha); peaches (Sphaerotheca pannosa, Monilia laxa); cereals (all major diseases); grapes (Uncinula necator, Guignardia bidwellii); sugar beet (Cercospora beticola, Erysiphe betae); maize (Helminthosporium turcicum); sunflowers (Phomopsis helianthi); oilseed rape (Pseudocercosporella capsellae, Pyrenopeziza brassicae); bananas (Mycosphaerella spp.).
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