Fluazuron
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Introduction: Fluazuron can be used as antiparasite, tick development inhibitor, insecticide, insect and acarine development inhibitor.Also can be used in cattle for controling of Boophilus microplus. The principle mode of action of fluazuron on the cattle-tick is by inhibition of chitin incorporation into tick cuticle. It is dangerous for the environment.
Common name: Fluazuron
Another name: Acatak; UNII-VB0PV6I7L6; Fluazuron [INN]; CHEBI:39374; etc.
Chemical name: 1-[4-chloro-3-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl]-3-(2,6-difluorobenzoyl)urea
Empirical formula: C20H10Cl2F5N3O3
Structural formula:
Mol. Weight: 506.21 g/mol
CAS No.: 86811-58-7
Specifications
Leading Fluazuron supplier
Fluazuron 95% TC
Fluazuron 25% SC
Fluazuron 10% WDG
Fluazuron 5% EC
Packing:
BULK PACKING
Powder: 25kg/Bag, 25kg/Drum, 50kg/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum etc.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized packing label
Fluazuron FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H400 (100%): Very toxic to aquatic life.
H410 (41.46%): Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to.
Supplemental Hazard Statements: none.
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rats is >5000 mg/kg. 2) Acute dermal LD50 for rats is >2000 mg/kg. 3) Acute inhalation toxicity LC50 (4 h) for rats is 5.99 mg/L. 4) Skin irritation: Non-irritating to skin (rabbits). 5) Eye irritation: Non-irritating to eyes (rabbits). 6) Skin sensitization for guinea pig: Non-sensitizer.
NOEL: (2 y) for mice is 4.3 mg/kg/day. Other Not genotoxic.
ADI 0-0.04 mg/kg b.w.
Classification:
WHO Classification: III (Slightly hazardous)
ECOTOXICOLOGY
Effect on birds: Acute oral LD50 (8 d) for Mallard is >2000 mg/kg. Effect on fish: Acute LC50 (96 h) for Rainbow trout is 15 mg/l. Effects on aquatic invertebrates: Acute EC50 (48 h) for Daphnia magna is 0.0006 mg/l. Effects on algae: Acute 72 hour EC50 is 27.9 mg/l. Effects on earthworms: Acute 14 day LC50 is 1000 mg/kg.
ENVIRONMENTAL FATE
Animals: Virtually no metabolism. Soil: Not investigated, environmental contamination is unlikely because of pour-on application. Plant: Not relevant.
Usage: Fluazuron was discovered by Ciba-Geigy. It is a insect growth regulator and broad spectrum antiparasitic substance used to control ticks in livestock, especially cattle.
Application: Biochemistry Interaction with chitin formation. Mode of action Systemic acarine growth regulator with contact and stomach action. Uses Strategic control of the cattle tick Boophilus microplus (including all known resistant strains) on beef cattle.
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