Cyflumetofen
   
Introduction: Cyflumetofen is highly effective against mites that have developed resistance to existing acaricides. In addition, Cyflumetofen is ideal to be used in IPM and resistance management program as it is notably safe to predatory mites and beneficial insects. Cyflumetofen is a new contact miticide active ingredient (ai) in the beta-ketonitrile chemical family labeled for control of all tetranychid mite life stages on numerous agricultural crops and ornamental plants. It is not active against non-tetranychid mites.
Common name: Cyflumetofen
Another name: 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoro methyl)phenyl]propanoate; CHEBI:81798; 2-methoxyethyl (RS)-2-(4-tert-butyl phenyl)-2-cyano-3-oxo-3-(alpha,alpha,alpha-trifluoro-o-tolyl)propionate; etc.
Chemical name:
2-methoxyethyl (RS)-2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-(,,-trifluoro-o-tolyl) propionate
Empirical formula: C24H24F3NO4
Structural formula:
Mol. Weight: 447.45 g/mol
CAS No.: 400882-07-7
Specifications
Leading Cyflumetofen supplier
Cyflumetofen 95% TC
Cyflumetofen 15% SC
Packing:
BULK PACKING
Powder: 25kg/Bag, 25kg/Drum, 50kg/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum etc.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized packing label
Cyflumetofen FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H317 (100%): May cause an allergic skin reaction.
H317: May cause an allergic skin reaction.
H410: Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P273: Avoid release to the environment.
P321: Specific treatment (see on this label).
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container in accordance with local/regional/national/ international regulations.
Supplemental Hazard Statements: none.
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rats is >2000 mg/kg. 2) Acute dermal LD50 for rats is >5000 mg/kg. 3) Acute inhalation toxicity LC50 (4 h) for rats is >2.65 mg/L. 4) Skin irritation: Non-irritating to skin (rabbits). 5) Eye irritation: Slightly irritating to eyes (rabbits). 6) Skin sensitization for guinea pig: Sensitizing (maximization test).
NOEL: (2 y) for rats is 16.5 mg/kg/day; (1 y) for dogs is 30 mg/kg/day. Other Unlikely to pose a carcinogenic risk from the diet. Unlikely to be genotoxic.
ADI (JMPR) 0-0.1 mg/kg b.w. [2014]
Classification:
WHO Classification: NL (Not listed)
EC Risk Classification: Xn - Harmful: R43
ECOTOXICOLOGY
Effect on birds: Acute oral LD50 (8 d) for Bobwhite quail is >2000 mg/kg. Effect on fish: Acute LC50 (96 h) for Rainbow trout is >0.63 mg/l. Effects on aquatic invertebrates: Acute EC50 (48 h) for Daphnia magna is >0.063 mg/l. Effects on algae: Acute 72 hour EC50 for Pseudokirchneriella subcapitata is 0.037 mg/l. Effects on bees: Contact acute 48 hour LD50 is >100 g/bee, oral acute 48 hour LD50 is >116 g/bee. Effects on earthworms: Acute 14 day LC50 is >1000 mg/kg.
ENVIRONMENTAL FATE
When cyflumetofen enters the terrestrial environment, it is expected to sorb to soil. Cyflumetofen is non-persistent in aerobic soil, where it undergoes microbial biotransformation. Under anaerobic (flooded) soil conditions, cyflumetofen was also found to be non-persistent. Photolysis is not expected to contribute to the transformation of cyflumetofen on soil, while hydrolysis can occur in moist soils and the rate increases with increasing pH.
Usage: Cyflumetofen is a novel benzoylacetonitrile acaricide developed by OAT Agrio Co., Ltd. It has excellent and highly selective efficacy against a variety of mites that attack fruits, nuts, vegetables, tea and ornamentals.
Application: Cyflumetofen is a compound in the benzoylacetonitrile class of chemistry. It interferes with energy production within cells and acts as an acaricide on contact with spider mites. Foliar application of cyflumetofen formulated as Nealta Miticide provides control of European red mite, twospotted spider mite and McDaniel spider mite on pome fruits, grapes, strawberries and tomatoes.
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