Introduction:Tolfenpyrad is a novel insecticide mainly for high-value market crops. Also shows some fungidal activity against powdery mildew. Tolfenpyrad is used to control aphids, leaf hoppers, scale, thrips, whitefly, potato psyllid, colorado beetle in vegetables particularly cruciferous leafy varieties, tea, fruit, indoor ornamentals except cut flowers.
Common name: Tolfenpyrad
Another name: OMI 88, Hachihachi EC, CHEBI:38628, NAI2302, NAI 2303, AK-86048, WPALTCMYPARVNV-UHFFFAOYSA-N
Chemical Name: 4-chloro-5-ethyl-2-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]pyrazole-3-carboxamide
Empirical formula: C21H22ClN3O2
Structural formula:
Mol. Weight: 383.876 g/mol
CAS No.: 129558-76-5
Specifications
Leading Tolfenpyrad supplier
Tolfenpyrad 150 g/L EC
Tolfenpyrad 200 g/L SC
Tolfenpyrad 300 g/L SC
Tolfenpyrad 10% WP
Tolfenpyrad 75% WDG
Tolfenpyrad 95% TC
Tolfenpyrad 96% TC
Tolfenpyrad 98% TC
Packing:
BULK PACKING
Powder: 25KG/Bag, 25KG/Drum, 50KG/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum ect.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized Packing label
Tolfenpyrad FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H302+H332: Harmful if swallowed or if inhaled
H302: Harmful if swallowed
H332: Harmful if inhaled
H400: Very toxic to aquatic life
H410: Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P301+P312: IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
P304+P312: IF INHALED: Call a POISON CENTER/doctor/... if you feel unwell.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P312: Call a POISON CENTER or doctor/... if you feel unwell.
P330: Rinse mouth.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Supplemental Hazard Statements: none
MAMMALIAN TOXICOLOGY
Acute toxicity:
1) Acute oral LD50 for rat: >386 a.i.mg/kg; 2) Acute dermal LD50 for Rabbit : 2000 a.i.mg/kg; 3) Inhalation LC50 (4 h) for rat: >2.21 a.i. mg/L; 4) Non-irritating to skin (rabbits); 5) slightly-irritating to eye (rabbits); 6) Not a skin sensitiser (guinea pigs). Tolfenpyrad was not carcinogenic and unlikely to be genotoxic or mutagenic, and tolfenpyrad is not teratogenic and neurotoxicity. No information on adverse health effects or poisoning in manufacturing plant personnel or in operators and workers exposed to tolfenpyrad was available.
ADI (JMPR): 0.006 mg/kg b.w.[2013]
Classification:
EC Risk Classification: Xn - Harmful: R20/22; N - Dangerous for the environment: R50/53.
ECOTOXICOLOGY
Effect on birds: high toxicity to birds, acute oral LD50 for Colinus virginianus is 83.0 a.i.mg/kg. Effect on fish: high toxicity to fish, acute 96 hour LC50 for rainbow trout is 0.049 a.i.mg/L. Effect on aquatic invertebrates: high toxicity to aquatic invertebrates, acute 48 hour EC50 for Daphnia magna is 0.008 a.i.mg/L. Effect on algae: moderate toxicity to algae, acute 72 hour EC50, growth is 1.36 a.i.mg/L. Effect on honeybees: high toxicity to honeybee, contact acute 48 hour LD50 is 0.188 a.i.g/bee; oral acute 48 hour LD50 is 0.252 a.i.g/bee.
ENVIRONMENTAL FATE
Tolfenpyrad moderately degrades under aerobic conditions (half-lives of 14-15 days in aerobic soil and aerobic aquatic water-sediment systems). Notably, Tolfenpyrad is known to degrade to several degradates which may be of toxicological concern. If these are of toxicological concern, then the persistence of Tolfenpyrad and its residues of concern would be considerably longer than that for the parent chemical alone. The bioaccumulation of Tolfenpyrad, a log Kow for Tolfenpyrad of 4.3 (MRID 47447701 in above cited document) in addition to the log Kow of 5.61 (MRID 48747601). Tolfenpyrad is recognized as not being Persistent in the atmosphere (the air photolysis half-life is 0.2 days). Long Range Transport was also investigated using the OECD Screening Pov (Overall Persistence) and LRTP (Long Range Transport Potential) Screening Tool for quantifying long range atmospheric transport potential of Tolfenpyrad. The OECD tool indicates a CTD (Characteristic Travel Distance) value of 59 km and Pov (Overall Persistence) of 34 days. Characteristic travel distance is defined as the distance to which 38 percent of the chemical has degraded in the system.
Usage: Tolfenpyrad is developed in 1988 by Mitsubishi Chemical Holdings. Tolfenpyrad is a high-effective and wide spectrum insecticide. Control object to effectively combat Lepidoptera, Hemiptera, Diptera pests and so on, It is mainly used for vegetables, fruit trees, flowers and tea leafs.
Application: Broad-spectrum insecticidal for Lepidoptera, Hemiptera, Beetles, Hymenoptera, Diptera pests and Mites. 1. Broad-spectrum insecticidal. Have good effect on egg, larva, and imago. 2. Quick acting. Pests will die immediately once processed. 3. Effect lasting longer with about 10days. 4. No interactive resistance. 5. Resistance to rain. Almost not affected by the rainfall. 6. Safe and environmental friendly.
