Tetrachlorvinphos
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Introduction: Tetrachlorvinphos is an organophosphate cholinesterase inhibitor that is used as an insecticide. It has low mammalian toxicity. Tetrachlorvinphos's production may result in its release to the environment through various waste streams; its use as an insecticide and acaricide will result in its direct release to the environment. Its use in the control of ticks and fleas on pets and pet sleeping areas and in collars and shampoos for direct treatment of pets will result in its release to the environment through various waste streams. Its use in cattle mineral licks will result in its direct release to the environment.
Common name: Tetrachlorvinphos
Another name: STIROFOS; Gardona; Stirophos; Rabon; Cis-Gardona; etc.
Chemical Name (IUPAC): (Z)-2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate
Structural formula:
Empirical formula: C10H9Cl4O4P
Mol. Weight: 365.96
CAS No.: 22248-79-9
Specifications
Leading Tetrachlorvinphos supplier
Tetrachlorvinphos 95% TC
Tetrachlorvinphos 50% WP
Packing
BULK PACKING
Powder: 25KG/Bag, 25KG/Drum, 50KG/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum ect.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized Packing label
Tetrachlorvinphos FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H332: Harmful if inhaled.
H341: Suspected of causing genetic defects.
H400: Very toxic to aquatic life.
H410: Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P202: Do not handle until all safety precautions have been read and understood.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Supplemental Hazard Statements: None.
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rats is >4000 mg/kg. 2) Acute percutaneous LD50 for rabbits is >1500 mg/kg. 3) Acute inhalation toxicity LC50 (4 h) for rats is 0.85 mg/l. 4) Skin irritation: Slightly irritating to skin (rabbits). 5) Eye irritation: Moderately irritating to eyes (rabbits). 6) Skin sensitization for guinea pig: Not a skin sensitiser.
NOEL: Chronic Feeding System NOEL for dogs is 3.13 mg/kg/day, carcinogen System NOEL for mice is 240 mg/kg/day. Other Not mutagenic, not carcinogenic.
ADI 0.004mg/kg b.w.
Classification:
WHO Classification: III (Slightly hazardous)
EC Risk Classification: Xn - Harmful: R21, R22; Xi - Irritant: R36.
US EPA Classification (formulation): III (Caution - Slightly toxic)
ECOTOXICOLOGY
Effect on birds: Acute oral LD50 for Mallard is >2000 mg/kg. Effect on fish: Acute LC50 (96 h) for Rainbow trout is 0.43 mg/l. Effects on aquatic invertebrates: Acute EC50 (48 h) for Daphnia magna is 0.002 mg/l. Effects on bees: Contact acute (48h) LD50 is >1.37 g/bee.
ENVIRONMENTAL FATE
If released to air, a vapor pressure of 4.210-8 mm Hg at 25 indicates tetrachlorvinphos will exist in both the vapor and particulate phases in the atmosphere. Vapor-phase tetrachlorvinphos will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 16 hrs. Particulate-phase tetrachlorvinphos will be removed from the atmosphere by wet or dry deposition. On exposure to UV radiation, tetrachlorvinphos underwent cis isomerization leading to a cis-trans equilibrium that was not altered by further irradiation. If released to soil, tetrachlorvinphos is expected to have low mobility based upon an estimated Koc of 2,000. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 1.810-9 atm-cu m/mole. Tetrachlorvinphos is not expected to volatilize from dry soil surfaces based upon its vapor pressure. A biodgradation half-life of <8 days in soil suggests that biodegradation may be an important fate process. If released into water, tetrachlorvinphos is expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. An estimated BCF of 17 suggests the potential for bioconcentration in aquatic organisms is low. The compound is slowly hydrolyzed. Occupational exposure to tetrachlorvinphos may occur through inhalation of dust and dermal contact with this compound at workplaces where tetrachlorvinphos is produced or used. Monitoring and use data indicate that the limited general population may be exposed to tetrachlorvinphos via inhalation of ambient air following field application and dermal contact with consumer products containing tetrachlorvinphos.
Usage: Tetrachlorvinphos was developed by Shell. It is an insecticide and acaricide for use against various pests of fruits, vegetables, ornamental plants, forest trees and livestock on agricultural and recreational areas.
Application: Tetrachlorvinphos is an organophosphate insecticide. It is currently applied dermally to livestock to control flies and mites; used as a feed-through (oral) larvicide in cattle, hogs, goats, and horses; in cattle ear tags to control flies; in poultry dust boxes to control poultry mites; and as paint on and sprays in poultry houses. Tetrachlorvinphos also is used as a dust/powder, aerosol, and pump spray on pets and in pet sleeping areas, and in collars and shampoos for direct treatment of pets. It is used as a spray to control nuisance and public health pests (flies) in and around refuse sites, recreational areas, and for limited outdoor use as premise sprays for fleas, ticks, chiggers, and mites, around kennels, yards, campgrounds, and parks, and along foot paths and roadways leading to such areas.
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