Flumethrin
  氟氯苯菊酯
Introduction: Flumethrin is used for the control of ectoparasites on livestock and domestic pets. It is also marketed for the diagnosis and control of varroatosis in bee hives.
Common name: Flumethrin
Another name: Bayticol, Bayvarol, Bayticol(TN), Flumethrin(Mixture of Diastereomers)
Chemical name: (RS)-α-cyano-4-fluoro-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-(EZ)-3-(β,4-dichlorostyryl)-2,2-dimethylcyclopropanecarboxylate
Empirical formula: C28H22Cl2FNO3
Structural formula:
Mol. Weight: 510.39 g/mol
CAS No.: 69770-45-2
Specifications
Leading Flumethrin supplier
Flumethrin 90% TC (cis:trans=9.6:0.4)
Packing:
BULK PACKING
Liquid: 200L/Drum, 20L/Drum, 10L/Drum ect.
SMALL PACKING
Liquid: 5L/Drum, 1L/Bottle, 500mL/Bottle, 250mL/Bottle, 100mL/Bottle, 50mL/Bottle etc.
Customerized Packing label
Flumethrin FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H301: Toxic if swallowed.
Precautionary statement(s)
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
P321: Specific treatment (see ... on this label).
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ...
Supplemental Hazard Statements: none
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rat: 41 a.i.mg/kg. 2) Acute dermal LD50 for rat: ˃2000 a.i.mg/kg. 3) Inhalation LC50 (4 h) for rat: 225 a.i. mg/L. 4) Not Irritating (rabbit). 5) Not Irritating (rabbit). 6) Not a skin sensitiser (guinea pigs). Reproductive Effects: None of the ingredients of the formulation have been shown to produce reproductive or teratogenic effects.
ADI: 0.004 mg/kg b.w./day
ECOTOXICOLOGY
Fish toxicity:
LC50 2.83 mg/L (96h) Trout (Oncorhynchus mykiss)
Concentrations of 0.5 ml/L are toxic to goldfish.
Daphnia toxicity: EC50 0.045 mg/L (48h) Water flea (Daphnia magna)
ENVIRONMENTAL FATE
Data on environmental fate were not required in relation to potential flumethrin residues in animal products from uses as an ectoparasiticide, but considered such information to be desirable for assessing the potential for undesirable environmental effects.
Usage: History Insecticide developed by Bayer AG. Patents DE 2932920 Manufacturers Bayer CropScience.
Application: Flumethrin is applied to cattle (including lactating cows), sheep, goats, horses and dogs as a spray, dip or pour-on treatment for the control of mange, mites, lice, biting lice and ticks. The only information provided on nationally approved uses (GAP) was on an Australian 75 g ai/l formulation for dips or sprays for cattle and horses, an Australian 1% ai pour-on for cattle and a UK 6% EC formulation for sheep dipping, all supported by labels. The submission made further general reference to a 6% EC for sprays or dips for sheep and dip for goats (Inveresk, 1996) but no labels, countries, withdrawal periods or treatment intervals were provided. The Inveresk reference to the 6% EC dip reported application rates of 44-66 mg ai/l to sheep (after milking if lactating) and 30-48 mg ai/l to goats. The application rate for sheep is consistent with the UK label. Flumethrin-impregnated plastic strips (3.6 mg/strip) are
also available for the control of Varroa in bee colonies, 2 to 4 strips per chamber. This use is approved in the UK (Inveresk, 1996), but again labels and other details were not provided.
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