Propisochlor
    异丙草胺
Introduction: Propisochlor is an aniline herbicide used to control annual grasses and broadleaf weeds in fields of corn, soybeans, sugarcane, peanuts and sunflower. It is a selective systemic herbicide used before emergence.
Common name: Propisochlor
Another name: Proponit; 2-Chloro-N-(2-ethyl-6-methylphenyl)-N- (isopropoxymethyl)acetamide; UNII-88248R3YQC; 88248R3YQC; etc.
Chemical name: 2-chloro-6'-ethyl-N-isopropoxymethylacet-ortho-toluidide
Empirical formula: C15H22ClNO2
Structural formula:
Mol. Weight: 283.80 g/mol
CAS No.: 86763-47-5
Specifications
Leading Propisochlor supplier
Propisochlor 92% TC
Propisochlor 50% EC
Propisochlor 72% EC
Packing:
BULK PACKING
Powder: 25kg/Bag, 25kg/Drum, 50kg/Drum etc.
Liquid: 200L/Drum, 20L/Drum, 10L/Drum etc.
SMALL PACKING
Powder: 1kg/Alu bag, 500g/Alu bag, 200g/Alu bag, 100g/Alu bag, 50g/Alu bag, 15g/Alu bag etc.
Liquid: 5L/Drum, 1L/Bottle, 500ml/Bottle, 250ml/Bottle, 100ml/Bottle, 50ml/Bottle etc.
Customerized packing label
Propisochlor FAO standard
Professional registration
HAZARDS IDENTIFICATION
Hazard statement(s)
H312 (89.29%): Harmful in contact with skin.
H317 (10.71%): May cause an allergic skin reaction.
H400 (10.71%): Very toxic to aquatic life.
H410 (10.71%): Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261: Do not breathe dust/fume/gas/mist/vapors/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P312: Call a POISON CENTER or doctor/... if you feel unwell.
P321: Specific treatment (see ... on this label).
P322: Specific measures (see ...on this label).
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P391: Collect spillage.
P501: Dispose of contents/container to an approved waste disposal plant.
Supplemental Hazard Statements: none.
MAMMALIAN TOXICOLOGY
Acute toxicity: 1) Acute oral LD50 for rats is 2290 a.i.mg/kg. 2) Acute dermal LD50 for rabbits is >2000 a.i.mg/kg. 3) Acute inhalation toxicity LC50 (4 h) for rats is >5.0 a.i.mg/L. 4) Skin irritation: Non-irritating to skin (rabbits). 5) Eye irritation: Non-irritating to eyes (rabbits). 6) Skin sensitization for guinea pig: Sensitiser (Buehler test).
NOEL: (2 y) for rats is 20 mg/kg/day; (18 m) for mice is 20 mg/kg/day. Other Not genotoxic.
ADI 0-0.025 mg/kg b.w.
Classification:
WHO Classification: NL (Not listed)
EC Risk Classification: Xn - Harmful: R21
US EPA Classification (formulation): III (Caution - Slightly toxic )
ECOTOXICOLOGY
Effect on birds: Acute oral LD50 for Japanese quail is >1562 a.i.mg/kg. Effect on fish: Acute LC50 (96 h) for Rainbow trout is 1.3 a.i.mg/l. Effects on aquatic invertebrates: Acute EC50 (48 h) for Daphnia magna is 14.0 a.i.mg/l. Effects on algae: Acute 72 hour EC50 for Scenedemus subspicatus is 0.012 a.i.mg/l. Effects on bees: contact acute 48 hour LD50 is >100 a.i.μg/bee, oral acute 48 hour LD50 is >111 a.i.μg/bee. Effects on earthworms: Acute 14 day LC50 is 248 a.i.mg/kg.
ENVIRONMENTAL FATE
Animals:In rats, most of applied radioactivity is excreted rapidly, mainly within 24 h.Soil:Decomposed by microbial action; typical soil DT50 10-15 d. Koc 333.3 (acid, sandy soil), 364.4 (acid, loamy soil), 493.5 (alkaline, loamy soil).
Usage: Propisochlor is a pre-emergence or pre-plant herbicide for control of annual grasses and some broad leaved weeds.
Application: Biochemistry: Protein synthesis inhibitor. Mode of action: Selective herbicide, absorbed by the shoots of germinating plants. Uses: Pre-emergence or pre-plant incorporated for control of annual grasses and some broad-leaved weeds in maize, sunflowers, soya beans, potatoes and peas (1.1-1.8 kg/ha). It can be used in beans and sweet lupins (1.1-1.8 kg/ha) and onions (1.4-1.8 kg/ha).
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